Thalidomide 4-fluoride( E3 ligase Ligand 4 )

Catalog No. M28566 CAS No. 835616-60-9

Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Thalidomide 4-fluoride
Note

Research use only, not for human use.
Brief Description

Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein.
Description

Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
In Vitro

——
In Vivo

——
Synonyms

E3 ligase Ligand 4
Pathway

Immunology/Inflammation
Target

IRAK
Recptor

Potassium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

835616-60-9
Formula Weight

276.223
Molecular Formula

C13H9FN2O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 300 mg/mL (1086.09 mM)
SMILES

Fc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Davies PJ, Thomas EA, Bornstein JC. Different types of potassium channels underlie the long afterhyperpolarization in guinea-pig sympathetic and enteric neurons. Auton Neurosci. 2006 Jan 30;124(1-2):26-30.

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